硕士生导师

联系方式：Email: iamjhliu@njtech.edu.cn

学术成绩

主要聚焦于光电生物传感方面的研究。近年来，以第一/通讯或合作者身份在Nat.Commun.、Adv. Mater.、ACSNano、Anal. Chem.、Biosens. Bioelectron.、ACS Appl. Mater. Inter.、Sensor Actuat B-Chem.、Chem. Commun.和Talanta等SCI 期刊发表论文50多篇，同行引用2000余次；主持国家自然科学基金三项、省级项目/开放课题/横向课题项目多项。担任Adv. Mater., Anal. Chem., Biosens. Bioelectron., ACS Appl. Mater. Inter., Sensor Actuat B-Chem., Talanta, Cellulose等期刊的审稿人。

研究方向

聚焦于光电生物传感研究，主要围绕多功能纳米材料展开（1）荧光酶联免疫试剂盒的研发；（2）智能健康柔性电子生物芯片的研发; 发展面上国家大健康的早期疾病诊断新技术和新方法。

代表性论文：

1. H. Yang, S. Zhu, L. Pang, Y. Ma, X. Liu, J. Liu*, Cu²⁺-triggered wavelength-tunable real-time in situ fluorogenic immunoassay for detection of cTnI in human serum, Sensors&Actuators: B. Chemical, 2024, 406,135388.

2. Q. Ci, H. Yang, Y. Bian, Z. Li, J. Liu*, J. Wei, N.Yang, J. Chen, L. Li *, C.Zhang*, An in situ fluorescent copolymer dots-based kit for the specific detection of monoamine oxidase-A in cell/tissue/human prostate cancer, Sensors&Actuators: B. Chemical, 2023, 397,134655.

3. W.Ma, L. Pang, J. Liu*, L. Wen, H. Ma, Y.Li*, Z. Xu, C. Zhang, and H. Yu*, MnO₄⁻‑triggered immediate-stable real-time fluorescence immunosensor with high response speed and low steady-state error, Analytical Chemistry. 2023, 95, 6323-6331.

4. Y. Sun#, L.Wen#, H.Ma#, W. Ma, Z. Fu, Yinhui Li*, C. Zhang, L. Li, J. Liu*, Engineering trienzyme cascade-triggered fluorescent immunosensor platform by sequentially integrating alkaline phosphatase, tyrosinase and horseradish peroxidase, Chinese Chemical Letters, 2023, 34, 107654.

5. F. Geng #, X. Liu #, T. Wei, Z. Wang, J. Liu*, C. Shao, G. Liu, M. Xu *, L. Feng*, An alkaline phosphatase-induced immunosensor for SARS-CoV-2 N protein and cardiac troponin I based on the in situ fluorogenic self-assembly between N-heterocyclic boronic acids and alizarin red S, Sensors&Actuators: B. Chemical, 2023, 378,133121.

6. Z. Hu, # C. Wei, # Q. Shi, # X. Hong, # J. Liu, #(共一) X. Zhou, J. Han, W. Cao, A. Gupta, X. Zhang, D.Wei*, Z. Fu*, W.Huang, Desymmetrization of N-Cbz Glutarimides through N-Heterocyclic Carbene Organocatalysis, Nature Communications, 2022, 13, 4042.

7. J. Liu*, G. Ruan, W. Ma, Y. Sun, H. Yu, Z.Xu, C.Yu, H. Li, C. Zhang,* and L. Li,* Horseradish peroxidase-triggered direct in situ fluorescent immunoassay platform for sensing cardiac troponin I and SARS-CoV-2 nucleocapsid protein in serum. Biosensors and Bioelectronics. 2022,198,113823.

8. C. Chen, G. Ruan, Y. Sun, L. Wang,* C. Zhang, J. Liu,* In situ Cu²⁺-triggered wavelength-tunable fluorescent sensor for highly sensitive sensing inorganic pyrophosphatase activity and its logic gate application, Sensors&Actuators: B. Chemical, 2021, 346,130439.

9. Y. Jiao, C. Du, L. Zong, X. Guo, Y. Han, X. Zhang, L. Li, C. Zhang, Q. Ju, J. Liu*, H. Yu*, W.Huang*, 3D vertical-flow paper-based device for simultaneous detection of multiple cancer biomarkers by fluorescent immunoassay, Sensors & Actuators: B. Chemical, 2020, 306,127239.

10. X. Guo, L.Zong,Y. Jiao,Y. Han, X. Zhang, J. Xu, L. Li, C. Zhang, Z. Liu, Q. Ju, J. Liu,* Z. Xu,* H. Yu,* W. Huang*, Signal-Enhanced Detection of Multiplexed Cardiac Biomarkers by a Paper-Based Fluorogenic Immunodevice Integrated with Zinc Oxide Nanowires, Anal. Chem. 2019, 91, 9300-9307.

11. Q. Zhang, D. Zhao, C. Zhang, J. Liu,* Z. An, X. Qin, Y. Gao,* S. Zhang, L. Li,* W. Huang. An effective signal amplifying strategy for copper (II) sensing by using in situ fluorescent proteins as energy donor of FRET. Sensor Actuat B: Chem., 2018, 259, 633-641.

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