李杰

男，汉族，副教授，硕士生导师

联系方式

办公地点：南京市新模范马路5号，南京工业大学丁家桥校区,D1602

电话：+86-15996273180

Email：iamjli@njtech.edu.cn

学习工作经历

2022.04至今：南京工业大学，柔性电子（未来技术）学院，副教授

2019.09 - 2021.09：澳门大学，健康科学学院，博士后

2017.07 - 2019.07：南京邮电大学，材料科学与工程学院，博士后

2011.09 - 2017.07：南京邮电大学，材料科学与工程学院，博士

研究方向

（1）内源性气体分子控释体系

（2）近红外分子影像制剂及光敏分子制备

（3）药物递送及肿瘤治疗体系

相关工作成果发表在Advanced Materials, Angewandte Chemie International Edition, Journal of the American Chemical Society, Small, Biomaterials等国际期刊中以一作/通讯作者身份发表14篇，总计38篇。参与编著《有机光电子材料在生物医学中的应用》。先后主持国家自然科学基金青年科学基金项目，南工大人才引进项目启动经费，中国博士后基金，江苏省博士后基金，并获得江苏省博士后日常资助项目资助；作为项目骨干参与国家自然科学基金面上项目,深圳市科技创新委员会项目（深港澳C类）以及校企合作项目等。

学术研成果：

1.Lisi Xie^†,Jie Li,^†Guohao Wang,^†Wei Sang, Mengze Xu, Wenxi Li, Jie Yan, Bei Li, Zhan Zhang, Qi Zhao, Zhen Yuan, Quili Fan, Yunlu Dai*. Phototheranostic metal-phenolic networks with anti-exosomal PD-L1 enhanced ferroptosis for synergistic immunotherapy,Journal of American Chemical Society,2022, 144, 787,

2.Jie Li, Lisi Xie, Wei Sang, Wenxi Li, Guohao Wang, Jie Yan, Zhan Zhang, Hao Tian, Quli Fan, Yunlu Dai*, A Metal-Phenolic Nanosensitizer Performs Hydrogen SulfideReprogrammed Oxygen Metabolism for Cancer Radiotherapy Intensification and Immunogenicity,Angewandte Chemie International Edition, 2022, 61, 202200830.

3.Jie Li; Lisi Xie; Bei Li; Chao Yin; Guohao Wang; Wei Sang; Wenxi Li; Hao Tian; Zhan Zhang; Xunajun Zhang; Quli Fan* and Yunlu Dai*; Engineering a Hydrogen Sulfide-based Nanomodulator to Normalize Hyperactive Photothermal Immunogenicity for Combination Cancer Therapy,Advanced Materials, 2021, 202008481.

4.Jie Li, Xiang Li, Yan Yuan, Qi Wang, Yunlu Dai, Wenjun Wang, Lin Li*, Xiaomei Lu*, Quli Fan* and Wei Huang. Efficient Polysulfide-based Nanotheranostics for Triple-negative Breast Cancer: Ratiometric Photoacoustics Monitored Tumor Microenvironment-initiated H2S Therapy,Small, 2020, 2002939.

5.Jie Li,Rongcui Jiang, Qi Wang, Xiang Li, Xiaoming Hu, Yan Yuan, Xiaomei Lu, Wenjun Wang, Wei Huang, Quli Fan^*.Semiconducting Polymer Nanotheranostics for NIR-II/Photoacoustic Imaging-Guided Photothermal Initiated Nitric Oxide/Photothermal Therapy,Biomaterials, 2019, 217, 119304.

6.Jie Li,Zhe Su, Changmin Yu*, Yan Yuan, Qiong Wu, Jie Liu, Bo Peng, Wenbo Hu, Xiaomei Lu*, Haidong Yu, Lin Li* and Wei Huang, Recent progress in the development of sensing systems for in vivo detection of biological hydrogen sulfide,Dyes and pigments, 2021, 192, 109451.

7.Jie Li, Wei Zhang, Wenhui Ji, Jiqing Wang, Nanxiang Wang, Wanxia Wu, Qiong Wu*, Xiyan Hou*, Wenbo Hu and Lin Li*, Near Infrared Photothermal Conversion Materials: Mechanism, Preparation and Photothermal Cancer Therapy Applications.Journal of Materials Chemistry B, 2021, 9, 7909-7926

8.Jie Li,Wenxi Li, Lisi Xie, Wei Sang, Guohao Wang, Zhan Zhang, Bei Li, Hao Tian, Jie Yan, Ye Tian, Zhenhua Li, Quli Fan, Lin Yu, and Yunlu Dai*. A Metal-polyphenolic Nanosystem with NIR-II Fluorescence-guided Combined Photothermal Therapy and Radiotherapy,Chemical Communications, 2021,DOI: 10.1039/d1cc04628d..

9.Jia Zhou, Wei Du, Tao Shao, Zheng Li, Duoteng Zhang, LanWang, Zhijie Fang,Jie Li*, Qiong Wu*, Chengwu Zhang,Lin Li*,Pyrimidine-Based Fluorescent Probe for Monitoring Mitophagy via Detection ofMitochondrial pH Variation,ChemBioChem,2022, e202200217.

10.Jie Li,†Lisi Xie,† Wei Sang, Wenxi Li, Guohao Wang, Hao Tian, Zhan Zhang, Jianhua Liu, Quli Fan, Yunlu Dai*. NIR-II-absorbing conjugated polymer-based theranostic agent for NIR-II fluorescence imaging-guided photothermal therapy acting synergistically with tumor microenvironment-responsive nitric oxide therapy,ChemPhysMater,2022, 1, 51.

11.Xinda Yang, Duoteng Zhang,Jie Li*, Wenhui Ji, Naidi Yang, Shunxin Gu, Qiong Wu, Qin Jiang *, Pengfei Shi* and Lin Li*. A Mitochondrion-targeting Mn(II)-terpyridine Complex for Two-Photon Photodynamic Therapy.Chemical Communications, 2020,56(63):9032-9035.

12.Jie Li, Yan Yuan, Gaoshan Zeng, Xiang Li, Zhen Yang, Xiaozhen Li, Rongcui Jiang, Wenbo Hu, Pengfei Sun, Qi Wang, Xiaomei Lu, Quli Fan*and Wei Huang*. A Water-soluble Conjugated Polymer with Azobenzol Side Chains Based on “Turn-on” Effect for Hypoxia Cell Imaging,Polymer Chemistry,2016,45(7):6890-6894.

13.Jie Li, Congcong Tian, Yan Yuan, Zhen Yang, Chao Yin, Rongcui Jiang, Wenli Song, Xiang Li, Xiaomei Lu, Lei Zhang, Quli Fan* and Wei Huang*. A Water-Soluble Conjugated Polymer with Pendant Disulfide Linkages to PEG Chains: A Highly Efficient Ratiometric Probe with Solubility-Induced Fluorescence Conversion for Thiol Detection.Macromolecules, 2015, 48(4): 1017–1025.

14.Gaoshan Zeng^†_,Jie Li^†, Hao Liang, Yan Yuan, Xiang Li, Chao Yin, Zhen Yang, Quli Fan, Xiaomei Lu*and Wei Huang*. A Water‐soluble Conjugated Polymer for Thiol Detection Based on "Turn‐off" Effect.Chinese Journal of Chemistry, 2015, 33(8):881-887.

著作

《有机光电子材料在生物医学中的应用》，2019，ISBN：9787030615459，第三章，参编。