杨乃娣，博士，助理教授

联系方式

办公地点：南京市新模范马路5号科创B楼514，南京工业大学丁家桥校区

邮箱: iamndyang@njtech.edu.cn

学习与工作经历

2019.04至今 南京工业大学 柔性电子（未来技术）学院 助理教授

2015.05–2018.12     新坡国立大学 医学院 博后研究员

2010.08–2015.04     新加坡国立大学 医学院 博士

2007.09–2010.03     浙江大学 医学院 硕士

2002.09-2007.06    鲁东大学  生命科学学院  学士

研究方向

1.  生物电子材料的抗癌作用及机制研究

2.  线粒体自噬探针的设计、合成及其在疾病诊疗中的应用研究

主要学术成绩

主要从细胞和分子生物学层面研究生物电子材料抗癌作用及机制，目前在Advanced Materials, Mol Neurobiol, Journal of Biological Chemistry和Autophagy等期刊上发表论文多篇。

代表作

1. Zhao Z, Li Z, Du F, Wang Y, Wu Y, Lim KL, Li L, Yang N*, Yu C*, Zhang C*. Linking Heat Shock Protein 70 and Parkin in Parkinson's Disease. Mol Neurobiol 2023.

2. Zhou Z, Zhang D, Du F, An W, Ge J, Yu C, Yang N*, Zhang C*, Lim K, Li L*. Design and Synthesis of a Mitochondrial-Targeted JNK Inhibitor and Its Protective Effect on Parkinson's Disease Phenotypes. Chembiochem 2023, 24(13): e202200748.

3. Wu Y^#, Zhao Z^#, Yang N^#, Xin C, Li Z, Xu J, Ma B, Lim KL, Li L, Wu Q, Yu C, Zhang C. Vitamin B12 Ameliorates the Pathological Phenotypes of Multiple Parkinson's Disease Models by Alleviating Oxidative Stress. Antioxidants (Basel) 2023, 12(1).

4. Yang N, Das D, Shankar SR, Goy PA, Guccione E, Taneja R. An interplay between BRD4 and G9a regulates skeletal myogenesis. Front Cell Dev Biol 2022, 10: 978931.

5. Xin C^#, Yang N^#, Ding Y, Han L, Zhou Z, Guo X, Fang Z, Bai H, Peng B, Zhang C, Li L. Mitochondria-Targeting Vitamin B3 Ameliorates the Phenotypes of Parkinson's Disease In Vitro and In Vivo by Restoring Mitochondrial Function, Adv Therap, 2022, 5.

6. Zhang C, Xue Y, Wang L, Wu Q, Fang B, Sheng Y, Bai H, Peng B*, Yang N*, Li L*. Progress on the Physiological Function of Mitochondrial DNA and Its Specific Detection and Therapy. Chembiochem 2022, 23(4): e202100474.

7. Guo X^#, Yang N^#, Ji W, Zhang H, Dong X, Zhou Z, Li L, Shen HM, Yao SQ, Huang W. Mito-Bomb: Targeting Mitochondria for Cancer Therapy. Adv Mater 2021, 33(43): e2007778. (ESI高被引论文)

8. Zhou B, Guo X, Yang N*, Huang Z, Huang L, Fang Z, Zhang C, Li L, Yu C*. Surface engineering strategies of gold nanomaterials and their applications in biomedicine and detection. J Mater Chem B 2021, 9(28): 5583-5598.

9. Wang L, Qin W, Chen D, Wang N, Zhang C, Fang Z, Fan B, Du W, Yang N*, Wu Q, Peng B*, Li L*. Design, synthesis and application of fluorogenic probe for detecting L-asparaginase in serum samples, Results in Chemistry 2021, 3.

10. Yang N*, Shen HM*. Targeting the Endocytic Pathway and Autophagy Process as a Novel Therapeutic Strategy in COVID-19. Int J Biol Sci 2020, 16(10): 1724-1731. (ESI高被引论文)

11. 汪蓝, 杨乃娣*, 陈鼎, 方海啸, 吴琼, 李林*.线粒体特异性检测与调控,化学通报 2020, 83(6): 488-496.

12. Yang N, Tan SH, Ng S, Shi Y, Zhou J, Tan KS, Wong WS, Shen HM*. Artesunate induces cell death in human cancer cells via enhancing lysosomal function and lysosomal degradation of ferritin. J Biol Chem 2014, 289(48): 33425-33441.